{"id":150,"date":"2015-12-16T10:26:53","date_gmt":"2015-12-16T13:26:53","guid":{"rendered":"https:\/\/investigacaoemdermatologia.com.br\/new\/?p=150"},"modified":"2016-01-11T14:29:56","modified_gmt":"2016-01-11T17:29:56","slug":"150","status":"publish","type":"post","link":"https:\/\/investigacaoemdermatologia.com.br\/?p=150","title":{"rendered":"Multiple confluent reddish nodules &#8211; Dermatology Practical &#038; Conceptual Journal"},"content":{"rendered":"<p>A 48-year-old fisherman from Amazonas (north of Brazil) developed a small papule on the anterior left leg after a traumatic injury with a piece of wood 20 years ago. Over the course of years, multiple large, confluent, reddish to brownish nodules with eventual ulceration came into being on the left leg and extended to the left thigh. There was a solitary, domed-shaped nodule on the right arm.<\/p>\n<p>Lobomycosis is a chronic infectious granulomatous disease of the dermis and hypodermis caused by the fungus <em>Lacazia loboi<\/em> [<a id=\"__tag_335434273\" class=\" bibr popnode tag_hotlink tag_tooltip\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/#b1-dp0303a05\">1<\/a>,<a id=\"__tag_335434269\" class=\" bibr popnode tag_hotlink tag_tooltip\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/#b2-dp0303a05\">2<\/a>]. There is no involvement of internal organs or external mucosas, but regional lymph nodes may be affected in 10\u201325% of the cases. [<a id=\"__tag_335434270\" class=\" bibr popnode tag_hotlink tag_tooltip\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/#b1-dp0303a05\">1<\/a>] It mainly affects adult males living in densely forested tropical areas that are in close contact with nature, such as farmers, tree tappers, miners, and workers of aquatic environments [<a id=\"__tag_335434265\" class=\" bibr popnode tag_hotlink tag_tooltip\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/#b1-dp0303a05\">1<\/a>,<a id=\"__tag_335434264\" class=\" bibr popnode tag_hotlink tag_tooltip\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/#b3-dp0303a05\">3<\/a>]. The original description of the disease by Jorge Lobo dates from 1930 and most cases have been reported in the northern Brazil, other countries of the Amazon region, Central America and Mexico. There have also been sporadic reports of the disease in United States, Europe and Canada, but at least some of these patients had been in South or Central America. Two autochthonous cases were recently reported in South Africa<\/p>\n<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791966\/\" class=\"su-button su-button-style-flat\" style=\"color:#FFFFFF;background-color:#AB2941;border-color:#892134;border-radius:5px\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color:#FFFFFF;padding:0px 16px;font-size:13px;line-height:26px;border-color:#c56a7a;border-radius:5px;text-shadow:none\"> Veja a publica\u00e7\u00e3o<\/span><\/a>\n","protected":false},"excerpt":{"rendered":"<p>A 48-year-old fisherman from Amazonas (north of Brazil) developed a small papule on the anterior left leg after a traumatic injury with a piece of wood 20 years ago. Over the course of years, multiple large, confluent, reddish to brownish nodules with eventual ulceration came into being on the left leg and extended to the &hellip; <a href=\"https:\/\/investigacaoemdermatologia.com.br\/?p=150\" class=\"more-link\">Continue lendo <i class=\"fa fa-arrow-circle-o-right\"><\/i><\/a><\/p>\n","protected":false},"author":5,"featured_media":349,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-150","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publicacoes"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multiple confluent reddish nodules - Dermatology Practical &amp; Conceptual Journal - Investiga\u00e7\u00e3o em Dermatologia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/investigacaoemdermatologia.com.br\/?p=150\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Joaquim Jeunon\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/investigacaoemdermatologia.com.br\\\/?p=150#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/investigacaoemdermatologia.com.br\\\/?p=150\"},\"author\":{\"name\":\"Joaquim Jeunon\",\"@id\":\"https:\\\/\\\/investigacaoemdermatologia.com.br\\\/#\\\/schema\\\/person\\\/55987b91349c9a519430fca2aa358f1b\"},\"headline\":\"Multiple confluent reddish nodules &#8211; 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